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- Taking some fat soluble vitamins together can optimise their efficacy, for example, when vitamin A and D are taken together, the expression of the RAR, VDR and RXR receptors and osteocalcin gene transcription are optimised. 3 This is likely because RXR is the main partner receptor for the vitamin A RAR and the vitamin D VDR receptors.3
- Fat soluble vitamin intake can be compromised.1 For example, up to 73% of Australians have insufficient vitamin D levels 4 Vitamin D from food sources is less biologically active and in insignificant amounts in most foods.1
- Vitamins A, D and K are essential for bone health.2 Vitamin A regulates the proliferation, differentiation and gene expression of chondrocytes, osteoblasts and osteoclasts which express the RXR receptor, shared by vitamin D. 5, 3 Both of these vitamins stimulate gene transcription of osteocalcin which binds calcium to new bone.6, 7 Vitamin K helps in the transport of calcium. 8
- A range of nutrient forms for improved efficacy. ADEK Essentials contains 2500 IU of vitamin A and the equivalent amount of betacarotene.9 ADEK Essentials also contains all eight isomers of vitamin E found in nature, including four tocopherols and four tocotrienols (alpha-, beta-, gamma- and delta-). 10
Always read the label. Follow the directions for use. If symptoms persist, consult your healthcare professional.